Articles tagged with: Medicine

Roentgen and Curie’s Contribution to Radiotherapy

Wilhelm-Roentgen

Wilhelm Roentgen

When German physicist Wilhelm Roentgen first discovered the X-ray in 1895, he probably didn’t know his discovery would eventually change the face of medicine forever.

Doctors and patients alike take radiation therapy (or radiotherapy) for granted in the modern era, but prior to its discovery, the primary means of cancer treatment was painful and risky surgery, which often took place without anesthesia. As far back as the second century AD, the Roman doctor Galen made records of “incurable” cancerous growths that would return even after a successful surgery, and many medical practitioners of the ancient era simply declared cancer an incurable disease.

However, when Wilhelm Roentgen discovered X-rays while experimenting with electricity, everything began to change. Roentgen discovered that these newly discovered “energy rays” could see through human flesh to the bone. He published a technical paper on his findings, which quickly spread through the medical community. The implications were clear and precedent-setting, and Roentgen eventually earned the Nobel Prize in Physics for his discovery in 1901 — the first such award to be given.

Marie-Curie

Marie Curie

Soon after, Marie Sklodowska — better known to history as Marie Curie — isolated polonium, the radioactive element that emits a particular kind of x-ray called gamma rays. Curie went on to uncover the properties of radium, eventually earning two Nobel Prizes for her work in the field. Today Curie is a more familiar name than Roentgen, and her legacy lives on in modern radiotherapy.

The discoveries of Roentgen and Curie would open the door for the first diagnostic X-rays in 1896, reducing the need for dangerous exploratory surgery to spot cancerous lesions and other medical symptoms. The first radiation treatment of cancer took place under the supervision of a medical student named Emil Grubbe, who became the world’s first radiation oncologist when he used x-rays to irradiate a patient with breast cancer.

By the time the nineteenth century drew to a close, radiation therapy was gaining ground in the United States and Europe. Claude Regaud, a Paris professor, revolutionized the burgeoning treatment when he experimented with slower radiation doses over several weeks, instead of the standard practices of a few larger radiation doses given in limited numbers. This method, called fractionation, is still used by oncologists to this day.

In the 1960s, many European radiotherapists and oncologists began to emigrate to the United States, making the U.S. the newfound center of radiation therapy. Where early x-ray machines had been primitive and limited in scope, new high-energy treatment machines called linear accelerators could penetrate much deeper into body tissues, reaching tumors that were previously impenetrable without causing too much damage to the skin. Linear accelerators became a popular and successful component of radiotherapy worldwide.

In the 1980s, the digital revolution brought new refinements to radiotherapy. Computer tomography allowed for more accurate delivery of x-rays and reduced damage to the surrounding tissues. Another technological development, known as Intensity Modulated Radiation Therapy (IMRT), further refined the process by allowing a computer to target a radiation dose to a patient’s body in three dimensions, further reducing tissue damage and making for fewer side effects. IMRT is now standard practice in the majority of all radiotherapy cases.

Image-Guided Radiation Therapy

Image-Guided Radiation Therapy

Today, radiotherapy continues to see new developments. Image-Guided Radiation Therapy, or IGRT, can produce high-quality scans of a patient’s body on the treatment table, meaning that doctors can get an up-to-date image of the patient just prior to treatment, instead of weeks or possibly months before. This means more accurate results and better survivability for the patient. Doctors and researchers continue to push the boundaries of cancer treatment, looking for new and effective means of curing – and eventually eradicating – the disease.

Thanks to Cancer Research UK for providing this post. Visit the site for more resources about breast cancer.

Today in History, April 13th

1598 King Henry IV of France signed the Edict of Nantes, granting rights to the Protestant Huguenots.
1742 George Frideric Handel’s “Messiah” was first performed publicly, in Dublin, Ireland.
1775 Lord North extends the New England Restraining Act to South Carolina, Virginia, Pennsylvania, New Jersey and Maryland. The act forbids trade with any country other than Britain and Ireland.

Lord North

Lord North

1861 At the start of the Civil War, Fort Sumter in South Carolina fell to Confederate forces as the Union commander, Maj. Robert Anderson, agreed to surrender in the face of relentless bombardment.
1865 Union forces under Gen. Sherman begin their devastating march through Georgia.
1919 British forces kill hundreds of Indian nationalists in the Amritsar Massacre.
1933 The first flight over Mount Everest is completed by Lord Clydesdale.
1941 German troops capture Belgrade, Yugoslavia.
1943 Franklin D. Roosevelt dedicates the Jefferson Memorial.
1945 Vienna falls to Soviet troops.
1954 Baseball Hall of Famer Hank Aaron made his major league debut with the Milwaukee Braves.

Hank Aaron

Hank Aaron

1960 The first navigational satellite is launched into Earth’s orbit.
1961 The U.N. General Assembly condemns South Africa because of apartheid.
1964 Sidney Poitier became the first black performer in a leading role to win an Academy Award, for “Lilies of the Field.”
1970 Apollo 13, four-fifths of the way to the moon, was crippled when a tank containing liquid oxygen burst.
1976 The U.S. Federal Reserve begins issuing $2 bicentennial notes.
1979 The world’s longest doubles ping-pong match ends after 101 hours.
1997 Tiger Woods, 21, became the youngest person to win the Masters Tournament.
1999 Jack Kervorkian was sentenced in Pontiac, Mich., to 10 to 25 years in prison for the second-degree murder of a man whose assisted suicide was videotaped and shown on “60 Minutes.”
2011 Ousted Egyptian President Hosni Mubarak and his two sons were detained for investigation of corruption, abuse of power and killings of protesters.
2011 A federal jury in San Francisco convicted Barry Bonds of obstruction of justice, but failed to reach a verdict on allegations that he’d used steroids and lied to a grand jury about it.

History of Malaria

I have found that my favorite part of school is trying to turn every class paper or essay into a history lesson. I’ve struck again! Science is easily the best subject to do this with. Diseases and inventions documented thousands of years ago; science’s affect on culture, countries, and economies; and how science has shaped the world are all interesting, scientific and historical. Whether you want to know about the history of the polio vaccination or how rubber was invented…I turn science into history here, at Hankering for History! While the history of malaria may not seem interesting, you may be surprised how it has affected America–especially on the battlefield.

Roman-Bath

A Roman Bath, an example of implementations to thwart malaria.

Credited by historians for having the largest impact on the fall of the Roman Empire and contributing to a large percentage of battlefield deaths during every war that America has ever participated in, malaria has outlasted all democracies, dictatorships, and monarchies. Malaria, an infectious disease caused by parasitic protists of the Plasmodium genus, has been around for tens of thousands of years. Malaria is most often passed human-to-human by the mosquito. Though documented historical references of malaria can be traced back as early as 1600 B.C.E., to the Vedic, it was the Greek physician Hippocrates that correctly drew the parallels between malaria and its ability to thrive in tropical areas.

“Roman fever” as it was called in fifth century C.E., was the collective name of the symptoms that were present then and still persist in today’s strands of malaria. Malaria presents symptoms starting with those similar to flu-like symptoms: headache, fever, and vomiting. The most prevalent symptom of malaria—and how it most stood apart from other illnesses—is paroxysm; this cyclical event brings on days of sudden coldness followed by days of fever. Even though medical professionals have been able to recognize the symptoms of malaria for thousands of years, it can only be properly diagnosed through microscopic examination of blood.

Malaria epidemics, transported by travelers, conquering armies, and through slave trade, plagued Europe for a long time until the Romans discovered a way to combat this parasitic disease. Malaria received its name from the Roman’s Italian phrase mal’ aria, which translates to “bad air.” The Romans discovered that malaria was prominent in areas around foul-smelling swamps; thus, the Romans created a drainage system to ensure that stagnant, malaria-infested waters would be flushed out of the city. While malaria is most commonly associated with poorer areas, it is ironic that it was a contributor to an invention that would allow cities and civilizations to become prosperous and thrive.

malaria-mosquito

It would not be until the 1880s that a string of scientist would discover the true cause and distribution method of malaria. Starting in 1880, Charles Louis Alphonse Laveran, a French army doctor, noted that the red blood cells of malaria patients were infected with parasites. In 1881, Carlos Finlay, a Cuban doctor, published evidence that the disease was possibly transmitted by the mosquito. In 1894, Sir Ronald Ross, a Scottish physician, and Sir Patrick Manson, the “father of tropical medicine,” provided unquestionable evidence that the mosquitos carried the blame for passing the malaria parasite through its salivary glands.

As noted earlier, malaria is commonly associated with poverty; however, economic trends now show that it is one of the primary causes of poverty. It has been estimated that the impact of malaria cost Africa $12 billion USD, annually. In countries where malaria is prevalent, it is responsible for 50% of illnesses that led to patients seeking medical attention. Another negative impact that malaria presents to the economy is in the production of counterfeit drugs. Specifically in Asian countries, counterfeit anti-malaria medicines have run rampant costing patients and medical facilities millions of dollars.

Malaria-history-world-war-2

World War II Malaria Posters

Even though malaria is now predominately found in sub-Saharan Africa and South Asia, it was once a major problem in every country; malaria plagued New World Americans from day one. In 1607, malaria plagued the colony of Jamestown and took the lives of half of the settlers. During the American Civil War, an estimated 1.2 million cases of malaria were reported (North and South combined). Even after the discovery of how malaria was contracted and spread, over 500,000 cases of malaria were reported in American soldiers during World War II. There was such a large concern over malaria that the CDC formed the Malaria Control in War Areas (MCWA), in 1942, to ensure that American military bases stayed malaria free.

With 3.3 billion of the world’s population living in “areas at risk of malaria transmission” and the World Health Organization estimating that 655,000 annual deaths are due to malaria, it is surprising that more resources are not funneled into a malaria vaccine. On average, 1,500 cases of malaria are reported every year in the United States of America. Until a vaccine is found, there are numerous safeguards to ensure that travelers do not contract malaria: anti-malaria medications, insecticide-treated nettings, and mosquito sprays are heavily recommended by the CDC.

Today in history, Dec 3rd!

Some of the great historical events that happened today in history, on December 3rd!

1468 Lorenzo the Magnificent and his brother Giuliano succeed their father, Piero de Medici, as rulers of Florence, Italy. Lorenzo the Magnificent

Today in history, Nov 11th!

Some of the great historical events that happened today in history, on November 11th!

1499 Pretender to the throne Perkin Warbeck is executed.
1620 Forty-one Pilgrims aboard the Mayflower, anchored off Massachusetts, signed a compact calling for a “body politick.”
1778 Indians, led by William Butler, massacre the inhabitants of Cherry Valley, N.Y.
1831 Nat Turner, a slave who led a revolt against slave owners, is hanged in Jerusalem, Virginia. Nat Turner
1889 Washington became the 42nd state.